HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Simona Caporali Selected Research

N,1,4,4- tetramethyl- 8- ((4- (4- methylpiperazin- 1- yl)phenyl)amino)- 4,5- dihydro- 1H- pyrazolo(4,3- h)quinazoline- 3- carboxamide

9/2012Down-regulation of the PTTG1 proto-oncogene contributes to the melanoma suppressive effects of the cyclin-dependent kinase inhibitor PHA-848125.
5/2010The cyclin-dependent kinase inhibitor PHA-848125 suppresses the in vitro growth of human melanomas sensitive or resistant to temozolomide, and shows synergistic effects in combination with this triazene compound.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown:


Simona Caporali Research Topics

Disease

12Melanoma (Melanoma, Malignant)
06/2019 - 10/2006
7Neoplasms (Cancer)
02/2020 - 02/2007
3Breast Neoplasms (Breast Cancer)
07/2008 - 10/2003
2Obesity
02/2020 - 08/2015
2Colonic Neoplasms (Colon Cancer)
08/2015 - 07/2008
1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL)
02/2020
1T-Cell Leukemia (Leukemia, T Cell)
02/2020
1Neoplasm Metastasis (Metastasis)
06/2019
1Leukemia
08/2015
1Carcinogenesis
08/2015
1Nevus (Nevi)
07/2014
1Hypersensitivity (Allergy)
03/2014
1Atherosclerotic Plaque (Atheroma)
09/2009
1Alzheimer Disease (Alzheimer's Disease)
09/2009
1Ataxia Telangiectasia (Louis Bar Syndrome)
07/2008
1Hyperthermia
02/2007
1Pituitary Neoplasms (Pituitary Adenoma)
12/2003

Drug/Important Bio-Agent (IBA)

7Pharmaceutical PreparationsIBA
06/2019 - 07/2008
5Proteins (Proteins, Gene)FDA Link
12/2017 - 09/2012
4dabrafenibIBA
06/2019 - 09/2016
4Temozolomide (Temodar)FDA LinkGeneric
05/2010 - 10/2006
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
06/2019 - 09/2016
3Estrogens (Estrogen)FDA Link
08/2004 - 10/2003
2Orlistat (Xenical)FDA Link
02/2020 - 08/2015
2Fatty Acid Synthases (Fatty Acid Synthase)IBA
02/2020 - 08/2015
2MicroRNAs (MicroRNA)IBA
06/2019 - 01/2019
2Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
01/2019 - 07/2008
2MethyltransferasesIBA
08/2015 - 02/2007
2DNA (Deoxyribonucleic Acid)IBA
08/2015 - 03/2014
2EnzymesIBA
08/2015 - 02/2007
2Cyclin-Dependent Kinases (cdk Proteins)IBA
09/2012 - 05/2010
2N,1,4,4- tetramethyl- 8- ((4- (4- methylpiperazin- 1- yl)phenyl)amino)- 4,5- dihydro- 1H- pyrazolo(4,3- h)quinazoline- 3- carboxamideIBA
09/2012 - 05/2010
2Estrogen Receptor alphaIBA
08/2004 - 10/2003
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
06/2019
1PIK 75IBA
01/2019
1Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA
01/2019
1VemurafenibIBA
01/2019
1trametinibIBA
12/2017
1Neuropilin-1IBA
09/2017
1Transcription Factors (Transcription Factor)IBA
09/2017
1Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
09/2017
1platelet-derived growth factor C (PDGF-C)IBA
09/2017
1Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
09/2016
1Matrix Metalloproteinases (MMPs)IBA
09/2016
1A-Form DNA (A-DNA)IBA
08/2015
1Oxaliplatin (Eloxatin)FDA LinkGeneric
03/2014
1Biomarkers (Surrogate Marker)IBA
03/2014
1EndonucleasesIBA
03/2014
1hexarelinIBA
09/2009
1EP80317IBA
09/2009
1Amyloid beta-PeptidesIBA
09/2009
1Phosphotransferases (Kinase)IBA
07/2008
1Small Interfering RNA (siRNA)IBA
07/2008
1Phenylalanine (L-Phenylalanine)FDA Link
02/2007
1Dacarbazine (DIC)FDA LinkGeneric
02/2007
1Melphalan (Alkeran)FDA LinkGeneric
02/2007
1O(6)-benzylguanineIBA
10/2006
1O(6)-Methylguanine-DNA MethyltransferaseIBA
10/2006
1phorbolIBA
08/2004
1ElementsIBA
08/2004
1Acetates (Acetic Acid Esters)FDA Link
08/2004
1Estrogen ReceptorsIBA
10/2003

Therapy/Procedure

4Therapeutics
02/2020 - 09/2017
2Drug Therapy (Chemotherapy)
03/2014 - 02/2007
1Drug Tapering
01/2019